Genomic Adaptation and Resilience to Climate Change (the GenARCC Project)

Funding period: 2022-2027
Leads: James Macklin, AAFC and Ian Bradbury, DFO
Total GRDI funding: $9,480,000

Globally, climate change continues to result in severe environmental perturbations with recent years being the warmest on record during the industrialized period. Within Canada, the climate continues to warm at a rate double the magnitude of global warming with northern Canada expected to experience the most extreme changes. There is a growing need for science advice on the adaptation of key species to climate change, and related economic and societal implications. Climate change represents a priority crossing the mandates of multiple federal science-based departments and agencies. Sixty-three scientists and their teams use genomics to assess climate change for the protection of Canada's biodiversity, ecosystem resiliency, food security, and health. They quantify genetic diversity in key species and populations, monitoring climate-associated change, and using genomics to predict future vulnerabilities in tundra, forest, aquatic, coastal and agricultural ecosystems.

Highlights

  • 5 year collaboration
  • 63 scientists and their teams
  • 8 federal departments and agencies

Objective

To use genomics to assess climate change for the protection of Canada's biodiversity, ecosystem resiliency, food security, and health

Envisioned Benefits

  • Science advice related to species response to climate change and related economic and societal implications
  • Quantified genetic diversity in key species and populations
  • Use of genomics to predict future vulnerabilities in forest, tundra, aquatic, coastal, and agricultural ecosystems

Publications

  • Ahmed R, Nasheri N. 2023. Animal reservoirs for hepatitis E virus within the Paslahepevirus genus. Veterinary Microbiology. Vet Microbiol 278:109618. https://doi.org/10.1016/j.vetmic.2022.109618
  • Alkie TN, Lopes S, Hisanaga T, Xu W, Suderman M, Koziuk J, Fisher M, Redford T, Lung O, Joseph T, Himsworth CG, Brown IH, Bowes V, Lewis NS, Berhane Y. 2022. A threat from both sides: Multiple Introductions of genetically distinct H5 HPAI viruses into Canada via both East Asia-Australasia/Pacific and Atlantic flyways. Virus Evolution 8(2). https://doi.org/10.1093/ve/veac077
  • Alkie TN, Cox S, Embury-Hyatt C, Stevens B, Pople N, Pybu MJs, Xu W, Hisanaga T, Suderman M, Koziuk J, Kruczkiewicz P, Nguyen HH, Fisher M, Lung O, Erdelyan CNG, Hochman O, Ojkic D, Yason C, Bravo-Araya M, Bourque L, Bollinger TK, Soos C, Giacinti J, Provencher J, Ogilvie S, Clark A, MacPhee R, Parsons GJ, Eaglesome H, Gilbert S, Saboraki K, Davis R, Jerao A, Ginn M, Jones MEB, Berhane Y. 2023. Characterization of neurotropic HPAI H5N1 viruses with novel genome constellations and mammalian adaptive mutations in free-living mesocarnivores in Canada. Emerging Microbes & Infections. Emerging Microbes and Infections 12(1):2186608. https://doi.org/10.1080/22221751.2023.2186608
  • Berhane Y, Joseph T, Lung O, Embury-Hyatt C, Xu W, Cottrell P, Raverty S. 2022. Isolation and Characterization of Novel Reassortant Influenza A(H10N7) Virus in a Harbor Seal, British Columbia, Canada. Infectious Diseases 28(7):1480-1484. https://doi.org/10.3201/eid2807.212302
  • Caliendo V, Lewis NS, Pohlmann A, Baillie SR, Banyard AC, Beer M, Brown IH, Fouchier RAM, Hansen RDE, Lameris TK, Lang AS, Laurendeau S, Lung O, Robertson G, van der Jeugd H, Alkie TN, Thorup K, van Toor ML, Waldenström J, Yason C, Kuiken T, Berhane Y. 2022. Transatlantic spread of highly pathogenic avian influenza H5N1 by wild birds from Europe to North America in 2021. Scientific Reports 12(1):11729. https://doi.org/10.1038/s41598-022-13447-z
  • Fisher M, Nebroski M, Davies J, Janzen E, Sullivan D, Lung O. 2023. Discovery and comparative genomic analysis of a novel equine anellovirus, representing the first complete Mutorquevirus genome. Scientific Reports 13(3703):1-10. https://doi.org/10.1038/s41598-023-30875-7
  • Kruczkiewicz P, Nguyen HH, Lung O. 2022. CFIA-NCFAD/nf-flu v3.1.0. Zonodo. https://zenodo.org/record/7011213#.ZBs5cXbMIuU
  • Lung O, Fisher M, Nebroski M, McGregor G, Schwantje H, Joseph T. 2022. Whole-Genome Sequence of Cervid atadenovirus A from the Initial Cases of an Adenovirus Hemorrhagic Disease Epizootic of Black-Tailed Deer in Canada. Microbiology Resource Announcements 11(1):e0066222. https://doi.org/10.1128/mra.00662-22
  • Pickering B, Lung O, Maguire F, Kruczkiewicz P, Kotwa JD, Buchanan T, Gagnier M, Guthrie JL, Jardine CM, Marchand-Austin A, Massé A, McClinchey H, Nirmalarajah K, Aftanas P, Blais-Savoie J, Chee HY, Chien E, Yim W, Banete A, Griffin BD, Yip L, Goolia M, Suderman M, Pinette M, Smith G, Sullivan D, Rudar J, Vernygora O, Adey E, Nebroski M, Goyette G, Finzi A, Laroche G, Ariana A, Vahkal B, Côté M, McGeer AJ, Nituch L, Mubareka S, Bowman J. 2023. Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission. Nature Microbiology 8,188. https://doi.org/10.1038/s41564-022-01298-3
  • Stefani F, Beguin J, Paré D, Morency MJ, Martineau C, Fortin JA, Thiffault N, Séguin A. 2023. Does wood mulch trigger microbially mediated positive plant-soil feedback in degraded boreal forest sites? A post hoc study. Frontiers in Plant Science. Volume 14. https://doi.org/10.3389/fpls.2023.1122445
  • Rabearison TJ, Poirier V, Gillespie A, Laganière J, DesRochers A. 2023. Increasing tree productivity does not translate into greater soil organic carbon storage. Forest Ecology and Management. Volume 535. https://doi.org/10.1016/j.foreco.2023.120884

Contact us

For additional information, please contact:
Genomics R&D Initiative
Email: info@grdi-irdg.collaboration.gc.ca